Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy PDF
Author: Barry J. Maron
Publisher: John Wiley & Sons
ISBN: 1405172568
Size: 66.33 MB
Format: PDF
Category : Medical
Languages : en
Pages : 128
View: 1043

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When there is a diagnosis of HCM in a family, this complete, easy-to-read guide is your essential resource for finding the answers to your many questions. In clear and straightforward language, it explains what hypertrophic cardiomyopathy is, what the symptoms are, and how it can be treated, as well as reviewing the genetic implications and offering candid lifestyle advice. Drawing on the expertise of Dr. Barry Maron, an internationally recognized authority on HCM, the book addresses major questions and concerns of both patients and families. Fully revised to reflect the latest developments, Hypertrophic Cardiomyopathy: For patients, their families and interested physicians, Second Edition, is a valuable source of straightforward advice and dependable information for everyone who is affected by HCM.

Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy PDF
Author: Folkert J. ten Cate
Publisher: Marcel Dekker Incorporated
ISBN:
Size: 23.53 MB
Format: PDF, Mobi
Category : Medical
Languages : en
Pages : 266
View: 7666

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Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy PDF
Author: Srihari S. Naidu
Publisher: Springer
ISBN: 3319924230
Size: 31.71 MB
Format: PDF, ePub, Mobi
Category : Medical
Languages : en
Pages : 479
View: 3493

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This extensively updated edition provides a comprehensive review of hypertrophic cardiomyopathy, the most common genetic disorder of the heart characterized by dysfunctional contractility at the sarcomere level. The disease produces abnormal and oftentimes focal hypertrophy on a macroscopic level that further impairs cardiac performance and may lead to life-threatening arrhythmias. This edition provides a practical approach, establishing evidence-based best practice for all scenarios. Hypertrophic Cardiomyopathy provides readers with key points and critical clinical pearls to assist them in managing patients. New chapters have been included on managing hypertension, sleep apnea, coronary artery disease, structural and congenital disease, nutrition and pharmacotherapies. All aspects of treatment are covered – medications, pacemakers and defibrillators, and invasive septal reduction therapy (both surgical myectomy and alcohol septal ablation) – in addition to genetics, family screening, lifestyle concerns, and athletic screening. The practical approach has been reinforced with an expanded emphasis on creating a Center of Excellence, how to facilitate the multi-disciplinary approach, and on case-based reviews and discussions, with each chapter ending with a post-test. This book is an essential text for cardiology professionals from trainee to board-certified physician, and includes important information for interventional cardiologists, cardiac surgeons, cardiac imagers, critical care physicians, sports medicine physicians, genetic counsellors, and electrophysiologists.

Genetic Evaluation Of Hypertrophic Cardiomyopathy

Genetic Evaluation of Hypertrophic Cardiomyopathy PDF
Author: Cristina Florescu
Publisher:
ISBN:
Size: 40.43 MB
Format: PDF, Mobi
Category : Medicine
Languages : en
Pages :
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Hypertrophic cardiomyopathy (HCM) is defined as left ventricular hypertrophy in the absence of abnormal loading conditions. In 50-60% of adolescents and adults with HCM, the disease is inherited as an autosomal dominant trait caused by mutations in cardiac sarcomere protein genes. The most cases are due to mutations in genes which determine the synthesis of myosin-binding protein C (MYBPC3) and beta-myosin heavy chain (MYH7). More rarely involved genes are those encoding myosin light chain 3 (MYL3), tropomyosin alpha-1 chain (TPM1), and cardiac troponins I and T (TNNI3, TNNT2). Mutations in genes encoding Z-disc or calcium-handling proteins account for less than 1% of cases. Multiple sarcomeric protein mutations are present in up to 5% of individuals. A further of 5% of patients have inherited metabolic or neuromuscular diseases, chromosome abnormalities, and genetic syndromes. HCM is characterized by a highly heterogeneous phenotype, highly variable intra- and interfamily expressivity and incomplete penetrance, therefore by a genotype-phenotype plasticity.

Heart Disease

Heart Disease PDF
Author: Eugene Braunwald
Publisher: W.B. Saunders Company
ISBN:
Size: 46.12 MB
Format: PDF, ePub, Mobi
Category : Cardiovascular system
Languages : en
Pages : 1996
View: 5830

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This reference on heart disease ranges from examination and circulatory function to diseases of the heart, and broader perspectives on heart disease and cardiologic practice. This edition includes 23 new chapters, covering such topics as coronary heart diseases in women, principles of cardiovascular, molecular and cellular biology, interventional catheterization techniques, haemostasis, and fibrinolysis and cardiovascular disease. There is also a chapter examining the influence of managed care and practice guidelines on treatment, diagnosis, therapy, and reimbursement.